Gastrointestinal manifestations of COVID-19 and possibility of feco-oral route of transmission
Keywords:coronavirus, gastrointestinal, feco-oral route
Covid-19 is a global health emergency originating from a small cluster of pneumonia like cases which spread to an extent to be regarded as a pandemic by WHO.in this review we discuss specifically the gastrointestinal manifestations of SARS CoV-2 positive patients in the published literature along with recent detection of SARS CoV-2 RNA in stool specimens and investigate the possible of feco oral route of viral transmission .
Iqbal MR. COVID-19 Pandemic: How, When and Where? Pakistan J Surg Med. 2020;1(2):127–32.
CDC. Coronavirus Disease 2019 (COVID-19) [Internet]. 2020 [cited 2020 Apr 29]. Available from: https://www.cdc.gov/coronavirus/2019-ncov/prevent-getting-sick/how-covid-spreads.html
WHO. Pneumonia of unknown cause – China [Internet]. World Health Organization. 2020 [cited 2020 Oct 10]. Available from: https://www.who.int/csr/don/05-january-2020-pneumonia-of-unkown-cause-china/en/
Sun P, Qie S, Liu Z, Ren J, Xi J. Clinical characteristics of 50466 patients with 2019-nCoV infection. medRxiv [Internet]. 2020 Jan 1;2020.02.18.20024539. Available from: http://medrxiv.org/content/early/2020/02/25/2020.02.18.20024539.abstract
Zhang J-J, Dong X, Cao Y-Y, Yuan Y-D, Yang Y-B, Yan Y-Q, et al. Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan, China. Allergy. 2020 Jul;75(7):1730–41.
Cheung KS, Hung IFN, Chan PPY, Lung KC, Tso E, Liu R, et al. Gastrointestinal Manifestations of SARS-CoV-2 Infection and Virus Load in Fecal Samples From a Hong Kong Cohort: Systematic Review and Meta-analysis. Gastroenterology. 2020 Jul;159(1):81–95.
Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet (London, England). 2020 Feb;395(10223):497–506.
Chen N, Zhou M, Dong X, Qu J, Gong F, Han Y, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet [Internet]. 2020 Feb 15;395(10223):507–13. Available from: https://doi.org/10.1016/S0140-6736(20)30211-7
Wong SH, Lui RN, Sung JJ. Covid-19 and the digestive system. J Gastroenterol Hepatol. 2020 May;35(5):744–8.
Xu L, Liu J, Lu M, Yang D, Zheng X. Liver injury during highly pathogenic human coronavirus infections. Liver Int Off J Int Assoc Study Liver. 2020 May;40(5):998–1004.
Lin L, Jiang X, Zhang Z, Huang S, Zhang Z, Fang Z, et al. Gastrointestinal symptoms of 95 cases with SARS-CoV-2 infection. Gut [Internet]. 2020 Jun 1;69(6):997 LP – 1001. Available from: http://gut.bmj.com/content/69/6/997.abstract
Rothe C, Schunk M, Sothmann P, Bretzel G, Froeschl G, Wallrauch C, et al. Transmission of 2019-nCoV Infection from an Asymptomatic Contact in Germany. Vol. 382, The New England journal of medicine. 2020. p. 970–1.
Holshue ML, DeBolt C, Lindquist S, Lofy KH, Wiesman J, Bruce H, et al. First Case of 2019 Novel Coronavirus in the United States. N Engl J Med [Internet]. 2020 Jan 31;382(10):929–36. Available from: https://doi.org/10.1056/NEJMoa2001191
Tang A, Tong Z-D, Wang H-L, Dai Y-X, Li K-F, Liu J-N, et al. Detection of Novel Coronavirus by RT-PCR in Stool Specimen from Asymptomatic Child, China. Emerg Infect Dis. 2020 Jun;26(6):1337–9.
Zhang W, Du R-H, Li B, Zheng X-S, Yang X-L, Hu B, et al. Molecular and serological investigation of 2019-nCoV infected patients: implication of multiple shedding routes. Emerg Microbes Infect. 2020;9(1):386–9.
Xu Y, Li X, Zhu B, Liang H, Fang C, Gong Y, et al. Characteristics of pediatric SARS-CoV-2 infection and potential evidence for persistent fecal viral shedding. Nat Med. 2020 Apr;26(4):502–5.
How to Cite
Copyright (c) 2021 Zubair Ahmed
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Authors retain the copyright of their manuscripts, and all Open Access articles are distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
Under CC-BY Liscence, you are free to
- Share — copy and redistribute the material in any medium or format
- Adapt — remix, transform, and build upon the material
- for any purpose, even commercially.
Please cite the author everytime you share. Thank You